Case 010096

Patterns of the mucosa surrounding the carcinomatous area.

Panoramic view of the region oriented toward the grossly depressed area. Note the inflammatory changes with atrophy. The sequence of the views below are representative of the mucosa right, middle, and left areas .

The epithelial lining discloses atypical foveolar hyperplasia.

Further, there is an increase of the atypia, with some features suggestive on intra-epithelial SRC.

Foveolar dysplasia in this area shows rupture of the basement membrane with invasion of the lamina propria.

Close-up on the previous fields.

Although, these features suggest in their presentation, SRC carcinoma in situ, the denomination of carcinoma in situ is by consensus avoided in gastric lesions. Severe dysplasia is the appropriate wording for such lesions. In this case, it is severe or high grade foveolar dysplasia(Fenoglio-Preiser in Gastrointestinal Pathology 2nd Ed.1999 p243).

Lymphnode status

References