F 30 ans Lésions papuleuses des extrémités prédominantes,
F 30 yo with papules on the extremities.
Genou
Knee
Trichrome
PAS - Ziehl Negatifs
Bilan clinique, IDR et Radio du Thorax, Négatifs
Clinical evaluation, PPD, Radiography negative.
Diagnostic Proposé:
Dermatite granulomateuse compatible avec une sarcoïdose
Proposed Diagnosis:
Granulomatous dermatitis consistent with sarcoidosis.
Arguments: Sarcoidal granulomas are discrete round to oval, and composed of epithelioid histiocytes and multinucleate giant cells which may be of either Langhans or foreign body type Granulomas may be present only in the superficial dermis or they may extend through the whole thickness of the dermis or subcutis Necrosis is not usually seen in granulomas but has been reported. Small amounts of fibrinous or granular material may be seen in some granulomas In most cases, the overlying epidermis is normal or atrophic. A diversity of clinical forms of cutaneous sarcoidosis occurs, chronic cutaneous lesions may be the only manifestation. For more details see: SARCOIDAL GRANULOMAS (Ref. Skin Pathology. David Weedon, 2nd Ed. Churchill-Livingstone)
Arguments:
Sarcoidal granulomas are discrete round to oval, and composed of epithelioid histiocytes and multinucleate giant cells which may be of either Langhans or foreign body type
Granulomas may be present only in the superficial dermis or they may extend through the whole thickness of the dermis or subcutis
Necrosis is not usually seen in granulomas but has been reported. Small amounts of fibrinous or granular material may be seen in some granulomas
In most cases, the overlying epidermis is normal or atrophic.
A diversity of clinical forms of cutaneous sarcoidosis occurs, chronic cutaneous lesions may be the only manifestation.
For more details see:
SARCOIDAL GRANULOMAS
(Ref. Skin Pathology. David Weedon, 2nd Ed. Churchill-Livingstone)
